Transcranial sonothrombolysis using high-intensity focused ultrasound: impact of increasing output power on clot fragmentation

Transcranial sonothrombolysis using high-intensity focused ultrasound: impact of increasing output power on clot fragmentation

BACKGROUND The primary goal of this study was to investigate the relationship between increasing output power levels and clot fragmentation during high-intensity focused ultrasound (HIFU)-induced thrombolysis. METHODS A HIFU headsystem, designed for brain applications in humans, was used for this project. A human calvarium was mounted inside the water-filled hemispheric transducer. Artificial...

High-Intensity Focused Ultrasound –

High intensity focused ultrasound (HIFU).

INTRODUCTION Curative treatments for localized prostate cancer, from least invasive to most invasive, include brachytherapy, cryosurgery, three-dimensional conformal radiation therapy, external beam radiation therapy, and radical prostatectomy. A patient with localized, low risk or intermediate risk prostate cancer who is diagnosed at an early age and receives one of these treatments has only a...

Characterization of high intensity focused ultrasound transducers using acoustic streaming.

A new approach for characterizing high intensity focused ultrasound (HIFU) transducers is presented. The technique is based upon the acoustic streaming field generated by absorption of the HIFU beam in a liquid medium. The streaming field is quantified using digital particle image velocimetry, and a numerical algorithm is employed to compute the acoustic intensity field giving rise to the obser...

Noninvasive Treatment of Breast Cancer Using High-Intensity Focused Ultrasound

Breast conserving surgery is a standard procedure for breast cancer since 1970. Now noninvasive therapy with few complications is preferred. High-intensity focused ultrasound (HIFU) has been developed to ablate solid tumor or cancer noninvasively. Its clinical outcome on breast cancer in China and Europe as well as the induced vascular destruction and immune response are summarized. In summary,...